Key takeaways
- Antenatal depression affects up to 30% of pregnancies worldwide, and only around one in five receive appropriate, timely support.
- Recent research is evaluating mind-body practices with the same scientific rigour traditionally reserved for clinical interventions.
- A new meta-analysis conducted at Kings College on research data across over 12,000 pregnant participants, found that psychological, non-psychological and combined interventions were comparable in their benefits.
- While yoga during pregnancy has long been popular, with clinicians often recommending it to their patients, the distinction here is looking at yoga in comparison to traditional interventions for perinatal mental health issues.
- Yoga therapy differs from a group class by tailoring practice to the individual, which matches the authors’ call for personalised treatment. It has not yet been compared with classes in research.
Understanding Matrescence and the Need for Holistic Support
Matrescence is the developmental transition into motherhood, encompassing the profound physiological, neuroendocrine, psychosocial and emotional changes of pregnancy and early parenthood. Navigating matrescence is a time of deep transformation, but also significant vulnerability.
While modern culture often idealises pregnancy, those of us holding space for pregnant patients and clients worldwide know that clinical reality tells a different story than social media spins: antenatal depression (AD) affects up to 30% of pregnant individuals globally.
Unaddressed antenatal depression also carries far-reaching downstream impacts on both maternal and infant wellbeing, including heightened risk of preterm birth, low birthweight, and postnatal depression.Â
Yet, only about 20% of affected individuals receive timely support due to long waiting lists, systemic barriers, and a lack of integrated care pathways.Â
For yoga therapists, as well as yoga teachers, this therefore presents a critical opportunity:
How, then, can our evidence-informed, mind-body tools serve as accessible, compassionate support during this vital life stage?
HappyMums: What the Latest Research Tells Us
Contemporary perinatal research is increasingly evaluating mind-body practices with the same scientific rigour traditionally reserved for clinical interventions.
The landmark 2026 meta-analysis of randomised controlled trials published in the Archives of Women’s Mental Health as part of the Horizon Europe-funded HappyMums project pools data from 115 studies involving over 12,000 pregnant participants, providing unprecedented large-scale findings which are meaningful for those of us working to serve our communities:
Standing Shoulder-to-Shoulder with Conventional Care
Specifically, the study found no significant difference in effectiveness between traditional psychological therapies (such as CBT) and non-psychological, mind-body practices like prenatal yoga and mindfulness. In short, yoga and mind-body tools proved equally as powerful as conventional psychological approaches.
Measurable Stress Reduction
Beyond emotional well-being, the research also confirmed a clear, measurable reduction in biological stress markers.Â
What the Numbers Look Like in Practice
In other words, on standard clinical questionnaires (like the PHQ-9 or the Edinburgh Postnatal Depression Scale), these findings translate to a tangible, meaningful easing of emotional distress and overall symptom burden during pregnancy.Â
The Physiology of Mind-Body Regulation in Pregnancy
To understand why yoga is capable of offering such effective support during pregnancy, we can therefore look at the physiological and hormonal pathways that may be engaged on the mat.
Downregulating the HPA Axis
First, structured mind-body practices may help soothe hypothalamic-pituitary-adrenal (HPA) axis hyperreactivity, buffering the body against excess stress hormones.
Autonomic Nervous System Regulation
Next, combining gentle physical movement (asana), regulated breathwork (pranayama), and mindful awareness (dhyana) directly shifts the autonomic nervous system out of fight-or-flight (sympathetic) and into the more restorative rest-and-digest response (parasympathetic).
Protecting Intergenerational Wellbeing
Finally, research highlights that maternal stress influences fetal development through inflammatory pathways. By providing tools that restore inner equilibrium, we create space for women to feel good, which in turn has a positive impact, and lasting benefits for both mother and child.
The Path to Better Perinatal Mental Health Care: Moving Forward Together
This exciting meta-analysis shows us the power of mind-body practices, such as yoga and mindfulness, for addressing perinatal mental health issues.
Overall, rather than viewing these practices as an isolated cure-all, its findings position them as valuable complementary pillars that work hand-in-hand with wider multidisciplinary care.Â
Yoga therapy, however, with its more individualised approach, psychotherapeutic skills and where practitioners also have a broader scope of practice, may offer even more, especially for women with challenging psychosocial or mental health issues, identified in pregnancy.
Ultimately, by working together as yoga therapists, teachers, and healthcare practitioners to bridge the gap between emotional support and physiological regulation, we can empower expectant and postnatal mothers with compassionate, accessible, and evidence-informed tools for lifelong wellbeing—and by extension, exert a positive influence on long-term infant welfare.
Yoga Therapy as Personalised, Primary Prevention
Pregnancy also represents a unique window of opportunity. Expectant parents are often deeply motivated to adopt health-protective habits, yet most have limited contact with specialist care early on.Â
As yoga therapists and teachers, our practices serve as:
- Accessible and inclusive tools that easily transcend socioeconomic and cultural barriers.
- Safe, low-intensity movement and breathwork that can be utilised as a first-line approach or alongside other care options.
- Somatic grounding spaces that translate complex nervous system care into a nourishing, lived experience.Â
The Importance of Clinical Expertise and Tailored Support in Practice
Moreover, yoga therapy is increasingly being recognised as a valid complementary intervention within mainstream maternity care, and as clinical guidelines evolve, yoga therapists are uniquely positioned to offer an empirically supported, patient-centred modality.
For example, the London Yoga Therapy Centre is one such case of this intervention in practice.Â
In particular, by integrating my background in obstetrics into our specialised yoga therapy offerings, we are able to ensure that every breath and movement honours the biological, psychosocial, and emotional realities of pregnancy and postpartum recovery.Â
A Footnote from Minded’s Founder, Heather Mason
The authors of the groundbreaking HappyMums meta-analysis called for treatment to be matched more closely to the individual, and this is where yoga therapy differs from a class.Â
While a pregnancy yoga class offers the same sequence of practices to a group, a yoga therapist works with one individual’s circumstances, using the pancha maya kosha model, which describes five interrelated layers of the person: the physical, the energetic, the mental, discernment and inner knowing, and joy.Â
By asking about their experience at each layer, a yoga therapist can then select and adapt practices, and refer on when a client’s needs fall outside their scope as a practitioner.
However, this individualised approach has not yet been compared with group classes in research.Â
Instead, it describes how yoga therapists work, and it is a question for future studies.
Two Ways You Can Explore Yoga Therapy in Practice
For qualified or trainee yoga therapists, and perinatal or mental health professionals with a foundation in yoga:
Sign up for The Minded Institute’s upcoming Online CPD: Yoga Therapy for Perinatal Mental and Physical Health, led by Dr. Claire Sandberg, a medical doctor and experienced yoga therapist.Â
Starting Thursday, 12 November, 2026, this IAYT-accredited CPD course offers a rare integration of biomedical knowledge, trauma-informed care, and yoga therapy expertise.
Learn more or book your place here.
For medical professionals or expectant mothers seeking evidence-informed care:
Explore specialised prenatal or postnatal yoga therapy sessions or book an initial consultation directly with Dr. Sangeeta Mittal, at The London Yoga Therapy Centre.
Whether seeking to manage prenatal anxiety, support nervous system regulation, or find community during the transition into motherhood, this South-West London-based private practice adheres to the highest standards of safety, transparency, and probity.
Appendix: Broadening the Evidence Base
Additionally, to maintain scientific objectivity, a robust body of peer-reviewed literature highlights the specific physiological and psychological mechanisms underpinning yoga as a therapeutic modality during the perinatal period.
Summary Table: Key Evidence Base
Study / Source |
Focus & Approach |
What This Means for Yoga Teachers & Therapists |
|---|---|---|
| Laijawala et al. (2026) | Large-scale analysis of mind-body interventions | Confirms that mind-body practices are just as effective as traditional psychological tools for prenatal mood support, alongside measurable biological stress reduction. |
| Radmark et al. (2023) | Research on Mindfulness-Based Childbirth & Parenting | Shows how structured mindfulness helps modulate the autonomic nervous system and soothe inflammatory pathways. |
| Zhang et al. (2024) | Review on exercise and prenatal yoga | Confirms that targeted physical activity and yoga significantly help ease depressive symptom severity during pregnancy. |
| Li et al. (2022) | Meta-analysis on mindfulness meditation in pregnancy | Highlights consistent, reliable reductions in prenatal anxiety and emotional distress. |
| Osborne et al. (2018) | Study on maternal stress and biological pathways | Underscores why early stress regulation is clinically essential for buffering inflammation and supporting healthy development. |
References
- Al-Abri, K., Edge, D. and Armitage, C.J., 2023. Prevalence and correlates of perinatal depression. Social Psychiatry and Psychiatric Epidemiology, 58(11), pp.1581–1590. Available at: https://doi.org/10.1007/s00127-022-02386-9.
- Association of the British Pharmaceutical Industry (ABPI), 2024. ABPI Code of Practice for the Pharmaceutical Industry 2024. London: PMCPA. Available at: https://www.pmcpa.org.uk [cite: 17, 18].
- Biaggi, A., Zonca, V. et al., 2025. Understanding, predicting, and treating depression in pregnancy to improve mothers’ and offspring’s mental health outcomes: the HappyMums study. Brain, Behavior, and Immunity – Health, 44, p.100961. Available at: https://doi.org/10.1016/j.bbih.2025.100961.Â
- Cattaneo, A., Biaggi, A. et al., 2025. Biopsychosocial predictors and therapeutic mechanisms in perinatal depression. Brain, Behavior, and Immunity – Health, 44, p.100961. Available at: https://doi.org/10.1016/j.bbih.2025.100961 [cite: 13, 14].
- Jones, L. (2023). Matrescence: On the Metamorphosis of Pregnancy, Childbirth and Motherhood. London: Allen Lane. Available at: https://lucyfjones.com/books/
- Laijawala, R., Priestley, K. et al., 2026. The evidence base of interventions to treat antenatal depression: a meta-analysis of randomized controlled trials. Archives of Women’s Mental Health, 29(1), pp.103–118. Available at: https://doi.org/10.1007/s00737-026-01723-0.Â
- Li, Y., Chen, J. et al., 2022. Effect of mindfulness meditation on depression during pregnancy: A meta-analysis. Frontiers in Psychology, 13, p.963133. Available at: https://doi.org/10.3389/fpsyg.2022.963133.Â
- National Institute for Health and Care Excellence (NICE), 2020. Antenatal and postnatal mental health: clinical management and service guidance [CG192]. London: NICE. Available at: https://www.nice.org.uk/guidance/cg192 [cite: 8, 14].
- Osborne, S., Biaggi, A. et al., 2018. Antenatal depression programs cortisol stress reactivity in offspring through increased maternal inflammation and cortisol in pregnancy: The Psychiatry Research and Motherhood Depression (PRAM-D) Study. Psychoneuroendocrinology, 98, pp.211–221. Available at: https://doi.org/10.1016/j.psyneuen.2018.06.017.Â
- Priestley, K., Laijawala, R. et al., 2026. HappyMums mobile application study protocol: Use of a smartphone application to gather data predictive of antenatal depression. BMJ Open, 16(2), p.e106978. Available at: https://doi.org/10.1136/bmjopen-2025-106978.Â
- Radmark, L., Osika, W. et al., 2023. Autonomic function and inflammation in pregnant women participating in a randomized controlled study of Mindfulness Based Childbirth and Parenting. BMC Pregnancy and Childbirth, 23(1), p.237. Available at: https://doi.org/10.1186/s12884-023-05528-2.Â
- Zhang, Z., Liu, Y.J. et al., 2024. The effects of exercise on antenatal depression: a systematic review and meta-analysis. Frontiers in Psychiatry, 15, p.1290418. Available at: https://doi.org/10.3389/fpsyt.2024.1290418 [cite: 16].




